Urine Analysis

Urine metal concentrations reflect excretion levels.

A comparison of an unprovoced (unchallenged) baseline urine with a Provocation urine following chelation allows an estimation regarding the body's metal load and the chelating agent's binding capability.

Baseline Urine

Elevated metal levels indicate immediate exposure. The renal system excretes metals without being provoked.
A low concentration on essential metals in urine may be caused by a reduced or inadequate dietary intake. It does not necessary indicate a nutritional deficiency.
If urine baseline results indicate low zinc excretion levels, supplementation is recommended before DMPS or EDTA chelation therapy, esp. in the presence of low blood and hair zinc levels. (Reason: EDTA and DMPS are strong chelators of zinc, and will bind this metal even if deficient)
To determine a nutritional deficiency, urine is not the ideal specimen

Information

The metal concentration in a provocation urine reflects the binding capacity of the chelating substance used, and the systems excretion ability. Combined, it is an indication of the degree of intoxication present.

We established DMPS-specific reference ranges and provide chelator-specific reference ranges, as available.

DMPS and Copper: the German medical toxicologist Dr. Daunderer determined that a urinary copper concentration of >500mcg/g Creatinine may be an indication of a reduced (masked) mercury elimination. The mass principle must be considered here: if one metal is present in a high amount, those present in lesser amounts may not be bound efficiently, hence excretion is reduced.

URINE CHALLENGE FOR TOXIC POLLUTANTS: WHY AND WHAT FOR?