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  MTM Newsletter N° 8 - June 2014
               
   
Laboratory News
Arsenic - Poison from below the Ground
Single Element Testing
Aluminum in Deodorants
Chelating Agents and the Blood Brain Barrier (BBB)
DMPS Capsules Heyl
The DTPAs - Facts provided by the CDC and the FDA
Tattoo Ink as a source of Metal Exposure
New eBook: Gentle Detox (Brief Summary)
Books and something to smile...
Medical Workshops and Conferences
Conferences and Workshops 2014
Studies and Analyses
Facts about the TACT Study
               
                           
   
                 
Laboratory News

Arsenic - Poison from below the Ground

Provocation tests showing high arsenic values often provoke questions. At times, the analytical accuracy is questioned, but assure you that our analytical confidence level is high and above average. For your information, we confirm all unusual test values through multiple, repeat testing.

Western populations are exposed to arsenic through food, especially grains. Algae products, bottled water, coffee, beer, rice and rice products, fish and vegetable may be a possible source of arsenic.

While concentrations of naturally occurring arsenic in ground water vary regionally due to a combination of climate and geology, ground water tests near waste disposal sites have shown high concentration of arsenic. European and American studies suggest that landfills and waste disposal sites both show high arsenic concentration.

For more information on arsenic in water, check:
http://www.microtraceminerals.com/en/environmental-analysis/water-analysis

http://water.usgs.gov/nawqa/trace/pubs/gw_v38n4

Single Element Testing
We test single elements in all types of samples. For information, contact service@microtraceminerals.com

Aluminum in Deodorants
An Iraqi study published in 2006 http://www.ncbi.nlm.nih.gov/pubmed/17037719 and numerous articles since have warned that aluminum is a cause of breast cancer. The German ministry of consumer affairs is now evaluating this potential risk. We will keep you posted.

It should be added that so-called natural deodorants may contain silver instead of aluminum, alcohol and/or various herbal ingredients.

We do test metals in varies diverse samples. For more information:
http://www.microtraceminerals.com/en/environmental-analysis/other-samples

Chelating Agents and the Blood Brain Barrier (BBB)
According to present knowledge the chelating agents most commonly used in environmental medicine and clinical metal toxicology (EDTA, DMSA, DMPS, DTPA) are not able to cross the BBB. Nevertheless, clinical observation indicates that neurological symptoms improve after detoxification therapy. The body’s internal metal homeostasis seems responsible.

The chelating agents mentioned first detoxify soft tissue. Fatty tissue are not first in line, but after soft tissues are largely metal-free, the redistribution of metals can and will start. For this undertaking, the body needs time- hence treatment pauses must be part of the treatment concept.

Our data indicate that after an appropriate pause, a follow-up provocation test often shows a rise in metal binding and excretion, meaning the next phase of the detoxification process has started. A comparison report as shown here confirms this concept.

Test Value Comparison Report

DMPS Capsules Heyl
Dr. Ruprecht, chief chemist and researcher of Heyl, Berlin, the manufacturer and distributor of DMPS has informed us that they have improved the product by eliminating the coloring agent titanium oxide. We are happy about that. Dr. Ruprecht notes however that pharmacists will still use the ‘old’ capsules in stock. If you use oral chelators, keep the coloring agent titanium oxide in mind when evaluating elevated Titanium levels in provocation tests.

The DTPAs - Facts provided by the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA)
DTPA (Diethylenetriamine pentaacetate) has been approved as an emergency medication for the chelation of some of the radioactive metals, and is approved for this use only.

DTPA comes in two forms: calcium (Ca-DTPA) and zinc (Zn-DTPA). Both forms work by tightly binding to radioactive plutonium, americium, and curium. When these radioactive materials are bound to DTPA, the DTPA-complex is excreted in the urine. DTPA works best when given shortly after radioactive plutonium, americium, and curium have entered the body. The more quickly radioactive material is removed from the body, the fewer and less serious the health effects will be.

When given within the first day after internal contamination has occurred, Ca-DTPA is more effective than Zn-DTPA. After 24 hours have passed, Ca-DTPA and Zn-DTPA are equally effective.

After 24 hours, DTPA binds less effectively to radioactive plutonium, americium, and curium. However, DTPA can still work to remove these radioactive materials from the body several days or even weeks after a person has been internally contaminated.

Ca-DTPA and Zn-DTPA do not treat contamination with radioactive iodine, uranium and neptunium, or the complications of radiation exposure (e.g., bone marrow suppression).

Ca-DTPA and Zn-DTPA should not be administered simultaneously. Ca-DTPA causes more loss of essential metals, such as zinc. Zn-DTPA increases the loss of iron and other essential metals. Both DTPAs increase magnesium and manganese binding and excretion.

More information:
http://www.bt.cdc.gov/radiation/dtpa.asp

We asked Dr. Ruprecht, research chemist at Heyl, Berlin about the DTPAs potential of crossing the BBB. His answer is: “No. DTPA can carry up to 5 negative charges, so a transition is not expected. Due to this high load, it can also not penetrate the intestinal mucosa. Therefore, it cannot be used for oral administration. It has a low bioavailability and must be injected."

Tattoo Ink as a source of Metal Exposure
A wide range of dyes and pigments can be used in tattoos and many come from materials like titanium dioxide and iron oxides to carbon black, azo dyes, naphthol derivatives, dyes made from ash, and other mixtures. Iron oxide and other metal pigments can migrate into deeper layers and may be distributed with the bloodstream, migrating to lymph nodes, causing inflammation. Cases of allergic reactions to tattoo inks, particularly nickel-containing colors have been medically documented.

During the past years, some countries applied governmental regulations concerning the labeling of tattoo ink and pigments. Common metals used in these dyes are nickel, chromium IV, barium, cobalt, and strontium. Even lead, cadmium and mercury compounds are used along with bromine, iodine and chlorine. Often the composition as well as the chemical structure of the used products is not known (Vasold et al., 2004). Thus, it is virtually impossible for tattoo studios to make statements of safety.

New eBook: Gentle Detox (Brief Summary)
Toxins accumulate over time and cause a wide variety of negative health effects. Nutritional detoxification and chemical balancing allows the removal of toxins that may cause metabolic problems, digestion disorders, skin weight problems, low energy, depression, autoimmune diseases, inflammatory or rheumatoid arthritis, Alzheimer's disease, Parkinson's disease and more.

eBook - Gentle Detox - The Natural Detoxification Program

Nutrients, certain minerals and trace elements, antioxidants and amino acids have the ability to detoxify an overburdened system. This booklet helps you understand environmentally-caused symptoms and allows you to select useful diagnostic tests. This booklet provides simple, easy and inexpensive self-help treatments.

Will be published on July 2014.

http://www.microtraceminerals.com/en/books-by-eblaurock-busch/e-book-gentle-detox

Books and something to smile...
If you go to Amazon.com you can locate one of the books by E.Blaurock-Busch, The No-Drug Guide to Better Health, first published in 1983 by Parker Publishing of Prentice Hall, which later was bought by Simon & Schuster. The cost: $2432.64! If this is too expensive, buy one of the 20 used books available for $0.01 plus shipping.

http://www.amazon.com/The-No-Drugs-Guide-Better-Health/dp/0136230903

                     
                         
   
                 
Medical Workshops and Conferences

International Conferences & Workshops 2014
09/19/2014 - 09/21/2014 IBCMT Workshop at the National Institute of Integrative Medicine
Melbourne, Australia (English)


Details under:
http://www.microtraceminerals.com/en/workshops

 
                         
   
                 
Studies and Analyses

Facts about the TACT Study
This 10-year, $31 million, National Institutes of Health (NIH) – funded study conducted under the auspices of the National Heart, Lung, and Blood Institute and the National Center for Complementary and Alternative Medicine was intended to provide a rigorous evaluation of the use of chelation therapy, thereby providing evidence to inform patients who may be seeking an as yet unproven therapy for prevention and treatment of coronary artery disease. However, the study has generated controversy since its inception and received varies interpretations.

  • 1. We contacted TACT principal investigator Dr Gervasio A Lamas (Mount Sinai Medical Center) regarding the interpretation of results.

    These are his comments:
    "When we broke the composite down to look at our secondary end points, we found that we had about a 40% reduction in total mortality, a 40% reduction in recurrent MI, and about a 50% reduction in mortality [in patients with diabetes]," Lamas said. Acknowledging that TACT was a "surprising" trial to begin with, "it turns out . . . the more detail you look into, the more extraordinary the effects.

    Prof Lamas also allowed us to print the following two slides from a previous lecture of his:

    TACT study - slide 1 - Design Overview - Factorial Trial The 1708 people tested were grouped as shown in slide 1
    (© Prof. Dr. Lamas, Columbia Universität, Maryland)

    Of the two groups who received additional high doses of vitamins in oral form, one was the EDTA group and the other the placebo group. The EDTA group who also received the vitamins as outlined above showed the most significant results (see green line in slide 2) and of this group, the diabetic patients responded best.

    TACT study - slide 2 - Primary Endpoint in Diabetes Subgroup
    (© Prof. Dr. Lamas, Columbia Universität, Maryland)

    For more information:
    http://www.microtraceminerals.com/en/chelation-newsarticles/edta

  • Dr. Richard Plumb, program chairman of ICIM (International College of Integrative Medicine) provided to us the following comments:

    - The TACT study “chelation therapy” is a safe modality
    - Why did Diabetics did best? Low intracellular magnesium is a well-known state of all diabetics, but it is unlikely just due to replacement of magnesium.
    - If a study on a new drug would show an 18% reduction in events, that drug would be the next billion dollar seller.

    We like to add that the study involved “NaMgEDTA Chelattherapie” and a recent study published in the European Journal of Clinical Nutrition indicates that Magnesium is inversely associated with serum C-reactive protein levels. The use of CaEDTA is not likely to provide such results, because the intravenous supply of high amounts of calcium would have Mg-antagonistic effects.

    http://www.microtraceminerals.com/en/metals-and-disease-research/inflammation
 
     
Coming Issue:
Oral chelators and how they work. CaEDTA causing redistribution of metals? Molybdenum as a copper chelator, and more.

We wish you all the best.

Your

E.Blaurock-Busch and Team
 
     
                   
                                 
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MTM Micro Trace Minerals GmbH - Director: Yvette Busch - Amtsgericht Nuernberg: HRB 21937 - Röhrenstrasse 20, 91217 Hersbruck, Germany - Phone: +49 9151-4332 - Email : service@microtraceminerals.com